NFL Week 1 Odds 2026: Spreads, Totals and Moneylines for Every Game

Favorites went 9-7 against the spread in Week 1, and the totals split eight overs and eight unders. Underdogs won four games outright, with the Cardinals beating the Chargers 26-14 as 10.5-point underdogs. Bears at Panthers combined for 96 points against a total of 47.5.

Lines are DraftKings’ spread, total and moneyline as listed on Covers on Sept. 4, before the week’s games kicked off, so they aren’t closing lines. The ESPN columns show the DraftKings spread and total on each game’s ESPN page, and the ATS and O/U results are graded against the Covers line. Two results change on ESPN’s numbers: Patriots at Seahawks is a push at SEA -3, and Cowboys at Giants goes over a total of 47.5.

Novig lists the same games as contracts and charges no fee on pre-game straight trades, so the contract price is the whole cost of a pre-game trade, with no -110 margin on top.

Matchup

Spread (Covers)

Spread (ESPN)

Total (Covers)

Total (ESPN)

Moneyline (Covers)

Final

ATS

O/U

NE at SEA

SEA -3.5

SEA -3

44.5

44.5

NE +154 / SEA -185

NE 10, SEA 13

NE covered

Under

SF at LAR

LAR -3.5

LAR -3.5

48.5

47.5

SF +164 / LAR -198

SF 27, LAR 7

SF covered

Under

TB at CIN

CIN -3.5

CIN -3.5

51.5

50.5

TB +170 / CIN -205

TB 27, CIN 33

CIN covered

Over

NO at DET

DET -7.5

DET -7

49.5

49.5

NO +250 / DET -310

NO 30, DET 31

NO covered

Over

NYJ at TEN

TEN -1.5

TEN -1.5

38.5

39.5

NYJ +110 / TEN -130

NYJ 23, TEN 10

NYJ covered

Under

BAL at IND

BAL -3.5

BAL -3

48.5

48.5

BAL -175 / IND +145

BAL 41, IND 23

BAL covered

Over

ATL at PIT

PIT -3.5

PIT -6.5

42.5

40.5

ATL +154 / PIT -185

ATL 13, PIT 20

PIT covered

Under

CHI at CAR

CHI -2.5

CHI -3

47.5

47.5

CHI -148 / CAR +124

CHI 59, CAR 37

CHI covered

Over

CLE at JAX

JAX -7.5

JAX -8.5

40.5

40.5

CLE +310 / JAX -395

CLE 10, JAX 34

JAX covered

Over

BUF at HOU

BUF -1.5

BUF -1.5

44.5

44.5

BUF -118 / HOU -102

BUF 36, HOU 31

BUF covered

Over

MIA at LV

LV -3.5

LV -3

40.5

40.5

MIA +164 / LV -198

MIA 13, LV 27

LV covered

Under

GB at MIN

MIN -1.5

MIN -2.5

45.5

46.5

GB -102 / MIN -118

GB 22, MIN 39

MIN covered

Over

WAS at PHI

PHI -5.5

PHI -6

44.5

43.5

WAS +180 / PHI -218

WAS 22, PHI 24

WAS covered

Over

ARI at LAC

LAC -10.5

LAC -8.5

46.5

47.5

ARI +455 / LAC -625

ARI 26, LAC 14

ARI covered

Under

DAL at NYG

DAL -2.5

DAL -3

48.5

47.5

DAL -148 / NYG +124

DAL 20, NYG 28

NYG covered

Under

DEN at KC

KC -2.5

KC -2.5

42.5

42.5

DEN +124 / KC -148

DEN 10, KC 31

KC covered

Under